Spravato is an FDA-approved nasal spray treatment that has been changing the way providers approach mental health care.

What Is Spravato?

Spravato is a prescription medication derived from ketamine. Unlike traditional antidepressants that may take weeks to show benefits, Spravato can begin to relieve symptoms much faster for some individuals. It is administered in a clinical setting under medical supervision, ensuring both safety and effectiveness.

What Conditions Is Spravato Used For?

Spravato is FDA-approved to treat:

• Treatment-Resistant Depression (TRD): For adults who haven’t found relief with at least two other antidepressants.
• Major Depressive Disorder (MDD) with Suicidal Thoughts or Actions: Helping to reduce severe symptoms when rapid relief is critical.

Some providers are also exploring its benefits for conditions such as PTSD, anxiety disorders, and chronic pain — though these uses may be considered off-label.

How Does Spravato Work?

Traditional antidepressants target neurotransmitters like serotonin. Spravato works differently. It affects the brain’s glutamate system, which plays a role in mood regulation and neural connections. This unique mechanism is believed to help “reset” certain pathways in the brain, offering new hope when other treatments haven’t worked.

What to Expect During Treatment:

Spravato treatment is always done in a clinic under medical supervision. Here’s what patients can expect:

1. Nasal spray administration by the patient, guided by a provider.
2. Observation period of about two hours, ensuring safety and comfort.
3. Ongoing treatment plan combined with therapy and/or oral antidepressants for the best outcomes.

Why Consider Spravato?

• Provides a new option when standard treatments have failed.
• May work faster than traditional antidepressants.
• Offers hope for those struggling with severe depression and suicidal thoughts.

Final Thoughts

Mental health recovery is not always a straight path. For those who feel stuck, Spravato may open the door to new possibilities. At Horizon Treatment Center, we are committed to offering innovative, evidence-based treatments to support each individual’s unique journey to healing.

Interested in learning more about Spravato and whether it might be the right fit for you or your loved one? Contact Horizon Treatment Center today.